How FPLC and HPLC Accelerate Drug Discovery and Protein Purification

Ana Lo
Published On: September 15, 2025

How FPLC and HPLC Accelerate Drug Discovery and Protein Purification

Ana Lo
Published On: September 15, 2025
Ana Lo
Published On: September 15, 2025

In the ever-evolving landscape of biotechnology, pharmaceutical development, and life sciences research, precision and reproducibility are paramount. Two key chromatographic techniques—Fast Protein Liquid Chromatography (FPLC) and High-Performance Liquid Chromatography (HPLC)—have become foundational tools in laboratories worldwide. Whether you’re separating complex mixtures, purifying high-value biomolecules, or validating compounds for clinical use, these systems form the bedrock of analytical and preparative workflows.

Why FPLC and HPLC Matter

FPLC is commonly employed for protein purification, leveraging aqueous buffers to isolate target molecules based on size, charge, or binding affinity. This technique is indispensable in proteomics, antibody development, and biologics production. Systems like the AKTA Pure, Avant 25, or Avant 150 from Cytiva (formerly GE) are widely regarded for their precision, flexibility, and scalability in both research and manufacturing environments.

HPLC, on the other hand, is used to separate, identify, and quantify components in a mixture. It’s a go-to method in drug development, quality control, environmental testing, and food safety. HPLC systems from manufacturers like Agilent, Shimadzu, or Waters are essential for delivering reproducible data and ensuring compliance with regulatory standards.


Applications in Modern Science

  • Drug Discovery & Development: HPLC is used throughout the drug development pipeline—from compound screening and stability testing to pharmacokinetics and formulation.
  • Protein Engineering & Vaccine Development: FPLC enables researchers to isolate specific proteins or antigens with high purity, which is critical in therapeutic design.
  • Clinical Diagnostics & QA/QC: Clinical and commercial labs rely on HPLC for consistency and traceability in the production of diagnostic kits and therapeutic products.
  • Academic Research: Universities and core facilities use both FPLC and HPLC for teaching, pilot studies, and collaborative projects, especially in life sciences and chemistry departments.

Purchasing with Confidence: Certified Systems from CGT/SSLLC

At Surplus Solutions, we understand that acquiring high-quality lab instrumentation doesn’t need to break your budget. We offer a robust inventory of certified refurbished FPLC and HPLC systems from industry-leading brands—available now and ready to ship.

Why Choose CGT/SSLLC for Your FPLC/HPLC Needs?

Certified & Tested– Every instrument is refurbished to OEM standards and undergoes comprehensive quality assurance protocols

Full Transparency– You receive detailed specifications, condition reports, and photos before you buy

Service & Support– Optional installation, service contracts, and maintenance support available

Speed of Procurement– Skip long OEM lead times with ready-to-ship equipment

Sustainability – Purchasing refurbished helps reduce electronic waste while supporting your research


Top Instruments Currently Available


Let’s Accelerate Your Research

Your next breakthrough starts with the right equipment. Whether you’re outfitting a new lab, replacing outdated systems, or scaling up your operation, SSLLC is your trusted vendor partner for premium chromatography solutions—backed by 20+ years of technical expertise and global service reach.

📩 Ready to discuss your needs or request a quote?

Contact us today at sales@ssllc.com, or visit our live inventory at www.ssllc.com.

Published On: September 15, 2025

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